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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1996 1
2000 1
2001 1
2003 1
2004 2
2005 1
2006 1
2008 3
2009 5
2010 1
2011 4
2012 2
2013 6
2014 3
2015 7
2016 3
2017 2
2018 5
2019 5
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2023 8
2024 4

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76 results

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Page 1
The CXCL8/IL-8 chemokine family and its receptors in inflammatory diseases.
Russo RC, Garcia CC, Teixeira MM, Amaral FA. Russo RC, et al. Expert Rev Clin Immunol. 2014 May;10(5):593-619. doi: 10.1586/1744666X.2014.894886. Epub 2014 Mar 29. Expert Rev Clin Immunol. 2014. PMID: 24678812
CXCL8 (interleukin-8) is a member of the chemokine family that acts on CXCR1 and CXCR2 receptors. CXCL1, CXCL2, CXCL3, CXCL5, CXCL6, and CXCL7 are also ELR+ chemokine members that bind to these receptors, especially CXCR2. ...There is substantial amount of experimental dat …
CXCL8 (interleukin-8) is a member of the chemokine family that acts on CXCR1 and CXCR2 receptors. CXCL1, CXCL2, CXCL3, CXCL5, CXCL6, …
Stromal Reprogramming through Dual PDGFRα/β Blockade Boosts the Efficacy of Anti-PD-1 Immunotherapy in Fibrotic Tumors.
Akiyama T, Yasuda T, Uchihara T, Yasuda-Yoshihara N, Tan BJY, Yonemura A, Semba T, Yamasaki J, Komohara Y, Ohnishi K, Wei F, Fu L, Zhang J, Kitamura F, Yamashita K, Eto K, Iwagami S, Tsukamoto H, Umemoto T, Masuda M, Nagano O, Satou Y, Saya H, Tan P, Baba H, Ishimoto T. Akiyama T, et al. Cancer Res. 2023 Mar 2;83(5):753-770. doi: 10.1158/0008-5472.CAN-22-1890. Cancer Res. 2023. PMID: 36543251
CAFs stimulated with PDGFs exhibited markedly increased expression of CXCL1, CXCL3, CXCL5, and CXCL8, which are involved in polymorphonuclear myeloid-derived suppressor cell (PMN-MDSC) recruitment. ...
CAFs stimulated with PDGFs exhibited markedly increased expression of CXCL1, CXCL3, CXCL5, and CXCL8, which are involved in polymorph …
Serum CXCL5 Detects Early Hepatocellular Carcinoma and Indicates Tumor Progression.
Laschtowitz A, Lambrecht J, Puengel T, Tacke F, Mohr R. Laschtowitz A, et al. Int J Mol Sci. 2023 Mar 10;24(6):5295. doi: 10.3390/ijms24065295. Int J Mol Sci. 2023. PMID: 36982370 Free PMC article.
In patients with HCC, CXCL5 serum levels were associated with tumor progression, and levels of CCL20 and CXCL8 with macrovascular invasion. Importantly, our study identified CXCL5, CXCL9, and CXCL10 as universal HCC markers, independent from underlying etiology of c …
In patients with HCC, CXCL5 serum levels were associated with tumor progression, and levels of CCL20 and CXCL8 with macrovascular inv …
CXCL5 promotes lipotoxicity of hepatocytes through upregulating NLRP3/Caspase-1/IL-1beta signaling in Kupffer cells and exacerbates nonalcoholic steatohepatitis in mice.
Qi J, Yan X, Li L, Qiu K, Huang W, Zhou Z. Qi J, et al. Int Immunopharmacol. 2023 Oct;123:110752. doi: 10.1016/j.intimp.2023.110752. Epub 2023 Aug 11. Int Immunopharmacol. 2023. PMID: 37573690
Previous studies have demonstrated that CXC motif chemokine ligand 5 (CXCL5) correlates positively with obesity and type 2 diabetes. This study is to explore the functional role of CXCL5 in the pathogenesis of NASH. ...Besides, neutralizing CXCL5 reduced lipi …
Previous studies have demonstrated that CXC motif chemokine ligand 5 (CXCL5) correlates positively with obesity and type 2 diabetes. …
Dampened Inflammation and Improved Survival After CXCL5 Administration in Murine Lupus via Myeloid and Neutrophil Pathways.
Fan X, Ng CT, Guo D, Lim F, Tan JC, Law A, Goh LH, Poon ZY, Cheung A, Kong SL, Tan M, Li S, Loh A, James A, Lim T, Chen J, Thumboo J, Hwang W, Low A. Fan X, et al. Arthritis Rheumatol. 2023 Apr;75(4):553-566. doi: 10.1002/art.42383. Epub 2023 Feb 22. Arthritis Rheumatol. 2023. PMID: 36240108
Pharmacokinetic studies were performed in Fas(lpr) mice and healthy Institute of Cancer Research mice. Efficacy of CXCL5 administration was demonstrated in Fas(lpr) mice, and the working mechanism of CXCL5 treatment was elucidated by flow cytometry, Luminex, and RNA …
Pharmacokinetic studies were performed in Fas(lpr) mice and healthy Institute of Cancer Research mice. Efficacy of CXCL5 administrati …
Expression and potential role of CXCL5 in the pathogenesis of intrauterine adhesions.
Fang ZA, He Y, Sun C, Zhan L, Zhou G, Wei B, Sun S. Fang ZA, et al. J Int Med Res. 2021 Mar;49(3):300060521997718. doi: 10.1177/0300060521997718. J Int Med Res. 2021. PMID: 33752504 Free PMC article.
We aimed to investigate the expression and mechanism underlying the role of CXCL5 in IUA. METHODS: Expression of CXCL5 in IUA was detected by immunohistochemistry in a rat model of IUA and by real-time PCR and western blotting in patients with IUA. ...CONCLUSIONS: …
We aimed to investigate the expression and mechanism underlying the role of CXCL5 in IUA. METHODS: Expression of CXCL5 in IUA …
Exercise training inhibits macrophage-derived IL-17A-CXCL5-CXCR2 inflammatory axis to attenuate pulmonary fibrosis in mice exposed to silica.
Jin F, Li Y, Gao X, Yang X, Li T, Liu S, Wei Z, Li S, Mao N, Liu H, Cai W, Xu H, Zhang H. Jin F, et al. Sci Total Environ. 2023 Dec 1;902:166443. doi: 10.1016/j.scitotenv.2023.166443. Epub 2023 Aug 21. Sci Total Environ. 2023. PMID: 37611700
Macrophage-derived IL-17A emerges as primary source and trigger for silica-induced pulmonary inflammation and fibrosis. Exercise training effectively inhibits IL-17A-CXC motif chemokine ligand 5 (CXCL5)-Chemokine (C-X-C motif) Receptor 2 (CXCR2) axis in silicotic mi …
Macrophage-derived IL-17A emerges as primary source and trigger for silica-induced pulmonary inflammation and fibrosis. Exercise trai …
Qilongtian ameliorate bleomycin-induced pulmonary fibrosis in mice via inhibiting IL-17 signal pathway.
Zhang Q, Luo T, Yuan D, Liu J, Fu Y, Yuan J. Zhang Q, et al. Sci Rep. 2023 Apr 12;13(1):6002. doi: 10.1038/s41598-023-31439-5. Sci Rep. 2023. PMID: 37045911 Free PMC article. Retracted.
Pulmonary fibrosis (PF) is a special type of pulmonary parenchymal disease, with chronic, progressive, fibrosis, and high mortality. ...Further studies indicated that QLT reduced the mRNAs and protein levels of interleukin 17 (IL-17), c-c motif chemokine ligand 12 ( …
Pulmonary fibrosis (PF) is a special type of pulmonary parenchymal disease, with chronic, progressive, fibrosis, and high mort …
Protective role of overexpressed MUC5AC against fibrosis in MHV-68-induced combined pulmonary fibrosis and emphysema mouse model.
He L, Feng QQ, Zhang Q, Zhang B, Wu SS, Gong JH. He L, et al. J Med Virol. 2020 Dec;92(12):3726-3735. doi: 10.1002/jmv.26094. Epub 2020 Jun 19. J Med Virol. 2020. PMID: 32557739
Meanwhile, a reduction of MHV-68 virus attenuated the expressions of chemokine (C-C motif) ligand 2 (CCL2), chemokine (C-X-C motif) ligand 5 (CXCL5), interleukin-13 (IL-13), and transforming growth factor-beta1 (TGF-beta1), and weakened airway inflammation and fibrosis …
Meanwhile, a reduction of MHV-68 virus attenuated the expressions of chemokine (C-C motif) ligand 2 (CCL2), chemokine (C-X-C motif) ligand 5 …
CXC-type chemokines promote myofibroblast phenoconversion and prostatic fibrosis.
Gharaee-Kermani M, Kasina S, Moore BB, Thomas D, Mehra R, Macoska JA. Gharaee-Kermani M, et al. PLoS One. 2012;7(11):e49278. doi: 10.1371/journal.pone.0049278. Epub 2012 Nov 16. PLoS One. 2012. PMID: 23173053 Free PMC article.
Recent studies from our group suggest that extracellular matrix (ECM) deposition and fibrosis characterize the peri-urethral prostate tissues of some men suffering from Lower Urinary Tract Symptoms (LUTS) and that fibrosis may be a contributing factor to the etiolog …
Recent studies from our group suggest that extracellular matrix (ECM) deposition and fibrosis characterize the peri-urethral prostate …
76 results